# $Id$ # # BioPerl module for Bio::DB::BioSQL::TermAdaptor # # Please direct questions and support issues to # # Cared for by Hilmar Lapp # # (c) Ewan Birney , 2002. # (c) Hilmar Lapp, hlapp at gmx.net, 2002. # (c) GNF, Genomics Institute of the Novartis Research Foundation, 2002. # # You may distribute this module under the same terms as perl itself. # Refer to the Perl Artistic License (see the license accompanying this # software package, or see http://www.perl.com/language/misc/Artistic.html) # for the terms under which you may use, modify, and redistribute this module. # # THIS PACKAGE IS PROVIDED "AS IS" AND WITHOUT ANY EXPRESS OR IMPLIED # WARRANTIES, INCLUDING, WITHOUT LIMITATION, THE IMPLIED WARRANTIES OF # MERCHANTIBILITY AND FITNESS FOR A PARTICULAR PURPOSE. # # POD documentation - main docs before the code =head1 NAME Bio::DB::BioSQL::TermAdaptor - DESCRIPTION of Object =head1 SYNOPSIS Give standard usage here =head1 DESCRIPTION Term DB adaptor =head1 FEEDBACK =head2 Mailing Lists User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to one of the Bioperl mailing lists. Your participation is much appreciated. bioperl-l@bioperl.org =head2 Support Please direct usage questions or support issues to the mailing list: I rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible. =head2 Reporting Bugs Report bugs to the Bioperl bug tracking system to help us keep track the bugs and their resolution. Bug reports can be submitted via email or the web: bioperl-bugs@bio.perl.org http://redmine.open-bio.org/projects/bioperl/ =head1 AUTHOR - Ewan Birney, Hilmar Lapp Email birney@ebi.ac.uk Email hlapp at gmx.net Describe contact details here =head1 APPENDIX The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _ =cut # Let the code begin... package Bio::DB::BioSQL::TermAdaptor; use vars qw(@ISA); use strict; # Object preamble use Bio::DB::BioSQL::BasePersistenceAdaptor; use Bio::DB::PersistentObjectI; use Bio::Ontology::Term; @ISA = qw(Bio::DB::BioSQL::BasePersistenceAdaptor); =head2 new Title : new Usage : Function: Instantiates the persistence adaptor. Example : Returns : Args : =cut sub new{ my ($class,@args) = @_; # we want to enable object caching push(@args, "-cache_objects", 1) unless grep { /cache_objects/i; } @args; my $self = $class->SUPER::new(@args); return $self; } =head2 get_persistent_slots Title : get_persistent_slots Usage : Function: Get the slots of the object that map to attributes in its respective entity in the datastore. Slots should be methods callable without an argument. Example : Returns : an array of method names constituting the serializable slots Args : the object about to be inserted or updated =cut sub get_persistent_slots{ my ($self,@args) = @_; return ("identifier","name","definition","is_obsolete","rank"); } =head2 get_persistent_slot_values Title : get_persistent_slot_values Usage : Function: Obtain the values for the slots returned by get_persistent_slots(), in exactly that order. The reason this method is here is that sometimes the actual slot values need to be post-processed to yield the value that gets actually stored in the database. E.g., slots holding arrays will need some kind of join function applied. Another example is if the method call needs additional arguments. Supposedly the adaptor for a specific interface knows exactly what to do here. Since there is also populate_from_row() the adaptor has full control over mapping values to a version that is actually stored. Example : Returns : A reference to an array of values for the persistent slots of this object. Individual values may be undef. Args : The object about to be serialized. A reference to an array of foreign key objects if not retrievable from the object itself. =cut sub get_persistent_slot_values { my ($self,$obj,$fkobjs) = @_; my @vals = ($obj->identifier(), $obj->name(), $obj->definition(), $obj->is_obsolete() ? 'X' : undef, $obj->can('rank') ? $obj->rank() : undef, ); return \@vals; } =head2 get_foreign_key_objects Title : get_foreign_key_objects Usage : Function: Gets the objects referenced by this object, and which therefore need to be referenced as foreign keys in the datastore. Note that the objects are expected to implement Bio::DB::PersistentObjectI. An implementation may obtain the values either through the object to be serialized, or through the additional arguments. An implementation should also make sure that the order of foreign key objects returned is always the same. Note also that in order to indicate a NULL value for a nullable foreign key, either put an object returning undef from primary_key(), or put the name of the class instead. DO NOT SIMPLY LEAVE IT OUT. Example : Returns : an array of Bio::DB::PersistentObjectI implementing objects Args : The object about to be inserted or updated, or undef if the call is for a SELECT query. In the latter case return class or interface names that are mapped to the foreign key tables. Optionally, additional named parameters. A common parameter will be -fkobjs, with a reference to an array of foreign key objects that are not retrievable from the persistent object itself. =cut sub get_foreign_key_objects{ my ($self,$obj,$fkobjs) = @_; my $ont; if(ref($obj) && $obj->ontology()) { $ont = $obj->ontology(); } else { $ont = "Bio::Ontology::OntologyI"; } return ($ont); } =head2 attach_foreign_key_objects Title : attach_foreign_key_objects Usage : Function: Attaches foreign key objects to the given object as far as necessary. This method is called after find_by_XXX() queries, not for INSERTs or UPDATEs. Example : Returns : TRUE on success, and FALSE otherwise. Args : The object to which to attach foreign key objects. A reference to an array of foreign key values, in the order of foreign keys returned by get_foreign_key_objects(). =cut sub attach_foreign_key_objects{ my ($self,$obj,$fks) = @_; my $ok = 1; if($fks && @$fks) { my $ont = $self->_ont_adaptor->find_by_primary_key($fks->[0]); $obj->ontology($ont) if $ont; $ok = $ont && $ok; } return $ok; } =head2 store_children Title : store_children Usage : Function: Inserts or updates the child entities of the given object in the datastore. The implementation can assume that all of the child objects are already Bio::DB::PersistentObjectI. Ontology terms have synonyms and dbxrefs as children. Example : Returns : TRUE on success, and FALSE otherwise Args : The Bio::DB::PersistentObjectI implementing object for which the child objects shall be made persistent. A reference to an array of foreign key values, in the order of foreign keys returned by get_foreign_key_objects(). =cut sub store_children{ my ($self,$obj,$fkobjs) = @_; my $ok = 1; my $saved_foreign_key_slot = $obj->foreign_key_slot(); $obj->foreign_key_slot(undef); # we possibly have synonyms to store $self->remove_synonyms($obj); foreach my $syn ($obj->get_synonyms()) { $ok = $self->store_synonym($obj,$syn) && $ok; } # we also possibly have db-xrefs to store my $dbladp = $self->db->get_object_adaptor("Bio::Annotation::DBLink"); foreach my $dbl ($obj->get_dbxrefs()) { # terms store dblinks as flat strings currently if(!ref($dbl)) { # some ontologies have URLs here or even whole sentences (check # out GO for an example); don't spend any effort here next if (index($dbl,"http") == 0) || (index($dbl," ") > 0); $dbl = $self->_build_dblink($dbl) unless ref($dbl); } # catch the dbxref non-compliant things that weren't caught in the # if condition before next if($dbl->database() eq "http" || (index($dbl->primary_id," ") > 0)); # now make persistent and serialize if necessary if(!($dbl->isa("Bio::DB::PersistentObjectI") && $dbl->primary_key())){ $dbl = $dbladp->create($dbl); } $ok = $dbl && $ok; # add the association between term and dbxref $dbl->adaptor->add_association(-objs => [$obj, $dbl]) if $dbl; } # done $obj->foreign_key_slot($saved_foreign_key_slot); return $ok; } =head2 attach_children Title : attach_children Usage : Function: Possibly retrieve and attach child objects of the given object. This is needed when whole object trees are supposed to be built when a base object is queried for and returned. An example would be Bio::SeqI objects and all the annotation objects that hang off of it. This is called by the find_by_XXXX() methods once the base object has been built. An ontology term has synonyms and dbxrefs as children. Example : Returns : TRUE on success, and FALSE otherwise. Args : The object for which to find and to which to attach the child objects. =cut sub attach_children{ my ($self,$obj) = @_; my $ok = 1; # get and attach the dbxrefs my $dbladp = $self->db->get_object_adaptor("Bio::Annotation::DBLink"); my $qres = $dbladp->find_by_association(-objs => [$obj,$dbladp]); while(my $dbl = $qres->next_object()) { # terms store dblinks as objects $obj->add_dbxref([$dbl]); } # retrieve the synonyms (synonyms aren't objects in their own right # in bioperl - although they could be) $ok = $self->get_synonyms($obj) && $ok; # done return $ok; } =head2 remove_children Title : remove_children Usage : Function: This method is to cascade deletes in maintained objects. Example : Returns : TRUE on success and FALSE otherwise Args : The persistent object that was just removed from the database. Additional (named) parameter, as passed to remove(). =cut sub remove_children{ return 1; } =head2 instantiate_from_row Title : instantiate_from_row Usage : Function: Instantiates the class this object is an adaptor for, and populates it with values from columns of the row. This implementation calls populate_from_row() to do the real job. Example : Returns : An object, or undef, if the row contains no values Args : A reference to an array of column values. The first column is the primary key, the other columns are expected to be in the order returned by get_persistent_slots(). Optionally, the object factory to be used for instantiating the proper class. The adaptor must be able to instantiate a default class if this value is undef. =cut sub instantiate_from_row{ my ($self,$row,$fact) = @_; my $obj; if($row && @$row) { if($fact) { $obj = $fact->create_object(); } else { $obj = Bio::Ontology::Term->new(); } # in order to store rank we need a persistent object - sooner or later # it will be turned into one anyway if (!$obj->isa("Bio::DB::PersistentObjectI")) { $obj = $self->create_persistent($obj); } # now populate $self->populate_from_row($obj, $row); } return $obj; } =head2 populate_from_row Title : populate_from_row Usage : Function: Instantiates the class this object is an adaptor for, and populates it with values from columns of the row. Example : Returns : An object, or undef, if the row contains no values Args : The object to be populated. A reference to an array of column values. The first column is the primary key, the other columns are expected to be in the order returned by get_persistent_slots(). =cut sub populate_from_row{ my ($self,$obj,$row) = @_; if(! ref($obj)) { $self->throw("\"$obj\" is not an object. Probably internal error."); } if($row && @$row) { $obj->identifier($row->[1]) if $row->[1]; $obj->name($row->[2]) if $row->[2]; $obj->definition($row->[3]) if $row->[3]; $obj->is_obsolete($row->[4]) if $row->[4]; $obj->rank($row->[5]) if $row->[5] && $obj->can('rank'); if($obj->isa("Bio::DB::PersistentObjectI")) { $obj->primary_key($row->[0]); } return $obj; } return undef; } =head2 get_unique_key_query Title : get_unique_key_query Usage : Function: Obtain the suitable unique key slots and values as determined by the attribute values of the given object and the additional foreign key objects, in case foreign keys participate in a UK. Example : Returns : One or more references to hash(es) where each hash represents one unique key, and the keys of each hash represent the names of the object's slots that are part of the particular unique key and their values are the values of those slots as suitable for the key. Args : The object with those attributes set that constitute the chosen unique key (note that the class of the object will be suitable for the adaptor). A reference to an array of foreign key objects if not retrievable from the object itself. =cut sub get_unique_key_query{ my ($self,$obj,$fkobjs) = @_; my $uk_h = {}; # UKs for ontology terms are identifier and (name,ontology) if($obj->identifier()) { $uk_h->{'identifier'} = $obj->identifier(); } elsif($obj->name()) { $uk_h->{'name'} = $obj->name(); if(my $ont = $obj->ontology()) { if(! ($ont->isa("Bio::DB::PersistentObjectI") && $ont->primary_key())) { $ont = $self->_ont_adaptor->create($ont); } $uk_h->{'ontology'} = $ont->primary_key(); } } return $uk_h; } =head1 Methods overriden from BasePersistenceAdaptor =cut =head1 Public methods specific to this module =cut =head2 remove_synonyms Title : remove_synonyms Usage : Function: Removes synonyms for the given ontology term. Example : Returns : TRUE on success, and FALSE otherwise. Args : The persistent term object for which to remove the synonyms (a Bio::DB::PersistentObjectI compliant object with defined primary key). =cut sub remove_synonyms{ my ($self,$obj) = @_; # do the error checking right here $obj->isa("Bio::DB::PersistentObjectI") || $self->throw("$obj is not a persistent object. Bummer."); $obj->primary_key || $self->throw("primary key not defined - cannot remove synonyms without"); # remove synonyms my $rv = $self->dbd->remove_synonyms($self,$obj); # done return $rv; } =head2 store_synonym Title : store_synonym Usage : Function: Stores a synonym for an ontology term. Example : Returns : TRUE on success, and FALSE otherwise. Args : The persistent term object for which to store the synonym (a Bio::DB::PersistentObjectI compliant object with defined primary key). The synonym to store (a scalar). =cut sub store_synonym{ my ($self,$obj,$syn) = @_; # do the error checking right here $obj->isa("Bio::DB::PersistentObjectI") || $self->throw("$obj is not a persistent object. Bummer."); $obj->primary_key || $self->throw("primary key not defined - cannot store synonym without"); # insert my $rv = $self->dbd->store_synonym($self,$obj,$syn); # done return $rv; } =head2 get_synonyms Title : get_synonyms Usage : Function: Retrieves the synonyms for an ontology term and adds them the term's synonyms. Example : Returns : TRUE on success, and FALSE otherwise. Args : The persistent term object for which to retrieve the synonyms (a Bio::DB::PersistentObjectI compliant object with defined primary key). =cut sub get_synonyms{ my ($self,$obj) = @_; # do the error checking right here $obj->isa("Bio::DB::PersistentObjectI") || $self->throw("$obj is not a persistent object. Bummer."); $obj->primary_key || $self->throw("primary key not defined - cannot get synonyms without"); # retrieve and add my $rv = $self->dbd->get_synonyms($self,$obj); # done return $rv; } =head1 Private methods These are mostly convenience and/or shorthand methods. =cut =head2 _ont_adaptor Title : _ont_adaptor Usage : $obj->_ont_adaptor($newval) Function: Get/set the ontology persistence adaptor. Example : Returns : value of _ont_adaptor (a Bio::DB::PersistenceAdaptorI object) Args : on set, new value (a Bio::DB::PersistenceAdaptorI object or undef, optional) =cut sub _ont_adaptor{ my $self = shift; return $self->{'_ont_adaptor'} = shift if @_; if(! exists($self->{'_ont_adaptor'})) { $self->{'_ont_adaptor'} = $self->db->get_object_adaptor("Bio::Ontology::OntologyI"); } return $self->{'_ont_adaptor'}; } =head2 _build_dblink Title : _build_dblink Usage : Function: Create a Bio::Annotation::DBLink object for a flat dbxref string. Example : Returns : A Bio::Annotation::DBLink instance Args : The dbxref as a flat string (DB:acc.version format) =cut sub _build_dblink{ my ($self,$dbxref) = @_; my ($db,$acc,$version) = $dbxref =~ /^([^:]+?):(.*)/; # only extract numerical versions, and only where there is only one dot # (EC numbers may come as dbxrefs - we don't want to chop off the last # digit there) my @accv = split(/\./,$acc); if((@accv == 2) && ($accv[1] =~ /^\d+$/)) { $version = $accv[1]; $acc = $accv[0]; } return Bio::Annotation::DBLink->new(-database => $db, -primary_id => $acc, -version => $version); } 1;